WeGuide Health Blog

A focused guide to how patient registries work as a real world evidence source, where regulators accept registry evidence, and what makes registry data fit for RWE.

A practical guide to eConsent for patient registries, covering dynamic and broad consent, reconsent, withdrawals, the features that matter, and the compliance and ethics behind long term registry consent.

A clear guide to disease registries: what they are, how they differ from patient registries, the main types with examples, and how they support research and drug development.

A clear comparison of patient registry vs clinical trial, covering design, intervention, data, duration, and regulatory role, with guidance on when to run a registry study and how the two work together.

A practical guide to rare disease registries: what they are, why they matter for natural history and drug development, the challenges of small dispersed populations, and how to run one well.

A practical, step by step guide to building a patient registry, covering objectives, governance and consent, the data model, technology, recruitment, and long term sustainability.

A practical buyer's guide to choosing patient registry software, covering the features that matter, build vs buy, compliance, and the questions to ask a vendor.

A practical guide to patient registries for sponsors, advocacy groups, and research teams, covering the definition, why they matter, the main types, how they differ from trials, how one works, and how to choose registry software.

A practitioner's guide to digital health technologies in clinical trials, covering the FDA's 2023 DHT framework, fit for purpose device selection, V3 validation, and the sponsor responsibilities that protect data integrity.

A focused guide to wearables in decentralised clinical trials: how remote sensors bridge data capture to the home, what they replace, where they sit in the DCT stack, and the data and logistics rules that decide whether the data holds up.

A practical guide to patient generated health data in clinical research: what PGHD is, its sources and examples, how it differs from clinician collected data, and how trials capture and govern it.

A practical comparison of Fitbit, Apple Watch, and Garmin for clinical research, weighing data access, validation, battery life, cost, and ecosystem so study teams can match the device to the measure and the population.

Wearable data is trustworthy in clinical trials when it is captured and validated well. A practical guide to wearable data quality, the V3 framework, wear time, missing data, and BYOD consistency.

A practical guide to digital endpoints in clinical trials: what they are, how they differ from digital biomarkers, how a measure becomes a validated and prespecified endpoint, what the FDA expects, and real examples across therapeutic areas.

A practitioner's guide to digital biomarkers in clinical trials, covering what a digital biomarker is, how they differ from digital endpoints, the main types by sensor and therapeutic area, the V3 validation framework, and how sponsors capture them.

A decision guide to BYOD vs provisioned devices in clinical trials, weighing cost, data quality, equity, and compliance, with clear advice on when to choose each model or a hybrid of both.

A practitioner's guide to wearables in clinical trials, covering device types, the data they capture, validation, BYOD vs provisioned models, and how sponsors turn sensor data into trusted endpoints.

Clinical trial dropout averages around 30% and is rising. Here are the benchmarks, the real reasons participants leave, and 12 ways to improve patient retention.

A practical guide to patient centricity in clinical trials: a clear definition, the disambiguation from related terms, the ROI evidence, and a lifecycle operating model plus maturity checklist to move from buzzword to a trial you can actually build.

A retention-framed look at decentralized clinical trials: the cited evidence by trial model, the burden-reducing mechanisms behind lower dropout, and where decentralisation does and does not help.

A practical framework for reducing patient burden in clinical trials, covering the five burden types, how to measure them, and the digital levers that cut each one.

A vendor neutral guide to choosing clinical trial patient engagement software, with a 9 point capability checklist, a build vs buy framework, and the CTMS and EDC distinction.

A stage by stage map of the clinical trial patient journey, with the engagement risk and the digital lever at each of the eight touchpoints where participants quietly fall away.

Patient engagement in clinical trials has two meanings: involving patients in trial design, and keeping enrolled participants active. Here is how both work.

A CTMS runs the operations of a trial and an EDC system captures the clinical data. Here is how they differ, where they overlap, and how they work together.

A clinical trial management system (CTMS) is the software that runs the operations of a trial: sites, timelines, budgets, and oversight. Here is what it does, how it differs from EDC and eTMF, and how to choose one.

Real world data is what you collect. Real world evidence is what you conclude. Here is the difference, a side by side comparison, and how RWD becomes RWE.

Teams running wearable studies finally have a sub-$100, screenless, all-day tracker option, and here is what the new Google Fitbit Air means for clinical research, from its sensors and accuracy to data export via the Google Health API.

eCOA validation actually covers four separate jobs: linguistic, equivalence, system, and psychometric. Here is what each one means, who owns it, and what FDA, EMA, ICH and TGA expect to see.

Most recruitment plans fail because they treat enrolment as a marketing problem, when it is really a design, experience, and retention problem rolled into one. Here are nine clinical trial recruitment strategies that work in the real world, with lessons from BRACE, GenV, and INHERIT on how to enrol faster and keep participants in the study.

Informed consent is more than the signature on the form, it has to hold up ethically, legally, and practically. We unpack the four principles every clinician and researcher needs to get right, with clear examples from clinical trials and the eConsent tools that support them.

Learn what real world evidence is, how it differs from real world data, where RWD comes from, and how regulators and research teams use RWE in practice.

Real world data in clinical trials explained: sources, regulatory context, use cases, and a practical guide to capturing RWD in your next study.

ePRO vs paper PRO compared. Peer reviewed evidence on cost, compliance and data quality, plus when paper still fits and how to choose for your next trial.

Learn how eConsent works in clinical trials, FDA and 21 CFR Part 11 requirements, benefits over paper, and how to roll out electronic informed consent.

A signed consent form isn't the same as informed consent, and most eConsent platforms miss that distinction. Here are 10 best practices for designing eConsent.

Learn what eCOA means in clinical trials, the four outcome types, benefits over paper, regulatory fit, and how to choose a platform that works.

What's the difference between eCOA and ePRO? Learn the key differences, when to use each in clinical trials, and practical tips from 100+ deployments.

Real time smart inhaler data integration helps researchers and clinicians improve asthma and COPD care. Track adherence, adjust treatments, and run better trials.

WeGuide’s new File Upload Question Type lets participants easily upload PDFs and images directly within forms, simplifying data entry and reducing errors.

WeGuide QR Code Login streamlines patient recruitment and enrollment, eliminating passwords and verification codes. Participants log in instantly with a quick scan: secure, fast, and effortless.

Discover how open ended questions enhance qualitative research. Learn how WeGuide's integrated approach, including the GenV case study, captures rich patient experiences that lead to discoveries.

WeGuide and Garmin Health announce a grant opportunity tailored for pioneering medical and wellbeing researchers and innovative digital health startups.

We are excited to bring you some fantastic additions to the WeGuide experience! Let us explain to you what that means...

Researchers can now collect ECG data remotely using Apple Watch and the WeGuide platform.

A look into how WeGuide, MCRI and philanthropic support empowers digital technology during COVID-19

Mobile data collection for your research study helps to reduce missing and bad data and opens up new

The pandemic has pushed healthcare providers to address two of the biggest challenges associated wit